A Review on Comprehensive Consequences of Gall Stones as Concomitant Disease in Hypothyroidism (CCCCH)
Published: 2023-09-08
Page: 151-156
Issue: 2023 - Volume 6 [Issue 1]
Sana Tabassum
St. Pauls College of Pharmacy, Affiliated to Osmania University, Turkayamjal, Hyderabad, Telangana, 501510, India.
Soujanya Durishetty
St. Pauls College of Pharmacy, Affiliated to Osmania University, Turkayamjal, Hyderabad, Telangana, 501510, India.
Mohammed Sabeeh Uddin
St. Pauls College of Pharmacy, Affiliated to Osmania University, Turkayamjal, Hyderabad, Telangana, 501510, India.
Thumukunta Komal
St. Pauls College of Pharmacy, Affiliated to Osmania University, Turkayamjal, Hyderabad, Telangana, 501510, India.
Are Anusha *
Department of Pharmacy Practice, St. Pauls College of Pharmacy, Affiliated to Osmania University, Turkayamjal, Hyderabad, Telangana, 501510, India.
*Author to whom correspondence should be addressed.
Abstract
This review investigates the potential correlation between hypothyroidism and gallstone disease, with a particular focus on subclinical hypothyroidism. The study explores the physiological factors that may contribute to gallstone formation in hypothyroid patients, including changes in bile flow and sphincter of Oddi dysfunction. The review also highlights the role of thyroid hormones in lipid metabolism and their potential impact on the composition of bile. The findings suggest a significant association between gallstone disorders and thyroid malfunction, particularly subclinical hypothyroidism. The review concludes that early identification and treatment of subclinical hypothyroidism could significantly reduce biliary stone disease in patients. regular monitoring of thyroid levels in hypothyroid individuals is recommended to prevent complications due to abnormal thyroid hormone levels.
Keywords: Hypothyroidism, gallstone disease, subclinical hypothyroidism, thyroid hormone level, biliary stone disease